In vitro effect of DDE exposure on the regulation of B-TC-6 pancreatic beta cell insulin secretion: a potential role in beta cell dysfunction and type 2 diabetes mellitus
Author:
Affiliation:
1. Center for Environmental Health Sciences, Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, MS, USA
Funder
Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15376516.2021.1950251
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1. Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis
2. Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity
3. Association of type 2 diabetes mellitus with plasma organochlorine compound concentrations
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