Beneficial effects of sodium glucose co-transporter 2 inhibitors (SGLT2i) on heart failure and cardiovascular death in patients with type 2 diabetes might be due to their off-target effects on cardiac metabolism
Author:
Affiliation:
1. Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippocration Hospital, Thessaloniki, Greece
2. Department of Veterans Affairs, George Washington University, Washington, DC, USA
Publisher
Informa UK Limited
Subject
Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism
Link
https://www.tandfonline.com/doi/pdf/10.1080/17584299.2016.1230316
Reference30 articles.
1. Research into the effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design
2. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
3. Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes
4. Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME®trial
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