Unfolding the Role of Splicing Factors and RNA Debranching in AID Mediated Antibody Diversification
Author:
Affiliation:
1. Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, Madhya Pradesh, India
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/08830185.2020.1815725
Reference113 articles.
1. Immunoglobulin Gene Diversification
2. RAG-1 and RAG-2, Adjacent Genes That Synergistically Activate V(D)J Recombination
3. Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
4. Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)
5. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
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