Altered expression of transcription factors IRF4 and IRF8 in peripheral blood B cells is associated with clinical severity and circulating plasma cells frequency in patients with myasthenia gravis

Author:

Zhang Yong1,Jia Xiao1,Xia Yan2,Li Hao1,Chen Fei1,Zhu Jie1,Zhang Xiuying3,Zhang Yanyan4,Wang YuZhong5,Xu Yanan1,Pan Meng1,Huang Xiaoyu6,Yu Tingyan6,Fu Linlin7,Xiao Chenghua1,Geng Deqin1

Affiliation:

1. Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China;

2. Department of Rehabilitation, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China;

3. Department of Neurology, Shenzhen Guangming New District Central Hospital, Shenzhen, China;

4. Department of Neurology, The Third People’s Hospital of Xuzhou, Xuzhou, Jiangsu, China;

5. Department of Neurology, Affiliated Hospital of Jining Medical college, Jining, Shandong, China;

6. Class 2014, Excellent Physician Class of Clinical Medicine Department, Xuzhou Medical University, Xuzhou, Jiangsu, China;

7. Department of Pathogenic Biology, Laboratory of Infection and Immunology, Xuzhou Medical University, Xuzhou, Jiangsu, China

Funder

National Nature Science Foundation of China

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Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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