Alterations in B cell development, CDR-H3 repertoire and dsDNA-binding antibody production among C57BL/6 ΔD−iD mice congenic for the lupus susceptibility loci sle1, sle2 or sle3-Reference-Cited by-同舟云学术

Alterations in B cell development, CDR-H3 repertoire and dsDNA-binding antibody production among C57BL/6 ΔD−iD mice congenic for the lupus susceptibility loci sle1, sle2 or sle3

Published:2017-01-02 Issue:1 Volume:50 Page:42-51
ISSN:0891-6934
Container-title:Autoimmunity
language:en
Short-container-title:Autoimmunity

Author:

Khass Mohamed¹²,Schelonka Robert L.³,Liu Cun Ren¹,Elgavish Ada¹,Morel Laurence⁴,Burrows Peter D.⁵,Schroeder Harry W.¹⁵

Affiliation:

1. Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA,

2. Genetic Engineering and Biotechnology Division, National Research Center, Cairo, Egypt,

3. Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA,

4. Department of Pathology, University of Florida, Gainesville, FL, USA, and

5. Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/08916934.2016.1272597

Reference24 articles.

1. Contributions of B cells to lupus pathogenesis

2. Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding.

3. Genetic Control of DH Reading Frame and Its Effect on B-Cell Development and Antigen-Specifc Antibody Production

4. Development of the Expressed Ig CDR-H3 Repertoire Is Marked by Focusing of Constraints in Length, Amino Acid Use, and Charge That Are First Established in Early B Cell Progenitors

5. The Peritoneal Cavity B-2 Antibody Repertoire Appears To Reflect Many of the Same Selective Pressures That Shape the B-1a and B-1b Repertoires

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