Phosphoprotein-based drug target activation mapping for precision oncology: a view to the future
Author:
Affiliation:
1. Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University , Manassas, Virginia, USA
Funder
No funding
Publisher
Informa UK Limited
Subject
Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/14789450.2018.1531709
Reference20 articles.
1. Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
2. Phosphorylated p-70S6K predicts tamoxifen resistance in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment
3. Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics
4. Molecular Analysis of HER2 Signaling in Human Breast Cancer by Functional Protein Pathway Activation Mapping
5. Hyperphosphorylation of RPS6KB1, rather than overexpression, predicts worse prognosis in non-small cell lung cancer patients
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