Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet

Author:

Hoffmann Mikael1,Vander Stichele Robert2,Bates David W3,Björklund Johanna4,Alexander Steve5,Andersson Marine L6,Auraaen Ane7,Bennie Marion8,Dahl Marja-Liisa6,Eiermann Birgit6,Hackl Werner9,Hammar Tora10,Hjemdahl Paul11,Koch Sabine12,Kunnamo Ilkka13,Le Louët Herve14,Panagiotis Papapetrou15,Rägo Lembit14,Spedding Michael16,Seidling Hanna M17,Demner-Fushman Dina18,Gustafsson Lars L619

Affiliation:

1. The NEPI Foundation - Swedish Network for Pharmacoepidemiology, Linköping University, Linköping, Sweden

2. Clinical Pharmacology Research Unit, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium

3. Center for Patient Safety Research and Practice, Division of General Internal Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA

4. Department of Computing Science, Umeå University, Umeå, Sweden

5. School of Life Sciences, University of Nottingham Medical School, Nottingham, UK

6. Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

7. Organisation for Economic Cooperation and Development (OECD), Paris, France

8. Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow, UK

9. Institute of Medical Informatics, UMIT-Private University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Austria

10. E-health Institute, Department of Medicine and Optometry, Linnaeus University, Kalmar, Sweden

11. Clinical Pharmacology Unit, Clinical Epidemiology Division, Department of Medicine, Karolinska Institutet, Stockholm, Sweden;

12. Health Informatics Centre, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden

13. The Finnish Medical Society Duodecim, Helsinki, Finland

14. Council for International Organizations of Medical Sciences (CIOMS), Geneva, Switzerland

15. Department of Computer and Systems Science, Stockholm University, Stockholm, Sweden

16. International Union of Basic and Clinical Pharmacology (IUPHAR), Paris, France

17. Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany

18. National Library of Medicine, National Institutes of Health, HHS, Bethesda, MD, USA

19. Swedish Institute for Drug Informatics (SIDI), Stockholm, Sweden

Funder

Swedish Research Council to cover costs for participation and presentation by foreign scientists at the workshop

Publisher

Informa UK Limited

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine

Reference91 articles.

1. Information Technology Comes to Medicine

2. Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region—Bridging the gap between knowledge and practice

3. Guidance for Industry. Patient-reported outcome measures: use in medical product development to support labeling claims. Food and Drug Administration. 2009 [cited 2020 July 23]. Available from: https://www.fda.gov/media/77832/download

4. Patient-reported outcome measures in skin cancer

5. Framework for FDA’s real-world evidence program. Food and drug administration; 2018 [cited 2020 July 23]. Available from: https://www.fda.gov/media/120060/download

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