Larotrectinib, a highly selective tropomyosin receptor kinase (TRK) inhibitor for the treatment of TRK fusion cancer
Author:
Affiliation:
1. Department of Pediatrics and Orthopedics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
2. Department of Medical Oncology, St. Vincent’s University Hospital & University College Dublin, Dublin, Ireland
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/17512433.2019.1661775
Reference42 articles.
1. NTRK gene fusions as novel targets of cancer therapy across multiple tumour types
2. TRKing Down an Old Oncogene in a New Era of Targeted Therapy
3. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia
4. TrkA alternative splicing
5. Testing algorithm for identification of patients with TRK fusion cancer
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