Discovery of antimicrobial compounds targeting bacterial type FAD synthetases

Author:

Sebastián María12ORCID,Anoz-Carbonell Ernesto123,Gracia Begoña34,Cossio Pilar56,Aínsa José Antonio234ORCID,Lans Isaías6,Medina Milagros12ORCID

Affiliation:

1. Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Zaragoza, Spain;

2. Institute of Biocomputation and Physics of Complex Systems (BIFI-IQFR and CBsC-CSIC Joint Units), Universidad de Zaragoza, Zaragoza, Spain;

3. Grupo de Genética de Micobacterias, Departamento de Microbiología, Medicina Preventiva y Salud Pública. Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain;

4. CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain;

5. Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt, Germany;

6. Biophysics of Tropical Diseases, Max Planck Tandem Group, University of Antioquia, Medellín, Colombia

Funder

Spanish Ministry of Economy, Industry and Competitiveness

FEDER

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference70 articles.

1. Trends in Antimicrobial Drug Development: Implications for the Future

2. Where are all the new antibiotics? The new antibiotic paradox

3. Prospects for new antibiotics: a molecule-centered perspective

4. WHO. Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline, including tuberculosis. WHO/EMP/IAU/2017.11 ed. World Health Organization: Geneva; 2017.

5. Antibacterial drug discovery in the resistance era

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