Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

Author:

Malinak David12ORCID,Dolezal Rafael12ORCID,Hepnarova Vendula23ORCID,Hozova Miroslava2,Andrys Rudolf1ORCID,Bzonek Petr13,Racakova Veronika4,Korabecny Jan23ORCID,Gorecki Lukas2ORCID,Mezeiova Eva2ORCID,Psotka Miroslav12ORCID,Jun Daniel23ORCID,Kuca Kamil12ORCID,Musilek Kamil12ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic

2. Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic

3. Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic

4. Faculty of Informatics and Management, Center for Basic and Applied Research, University of Hradec Kralove, Hradec Kralove, Czech Republic

Funder

Czech Science Foundation

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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