From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica

Author:

Ottaviani Alessio1,Welsch Joshua2,Agama Keli3,Pommier Yves3,Desideri Alessandro1ORCID,Baker Bill J.2,Fiorani Paola14

Affiliation:

1. Department of Biology, University of Rome Tor Vergata, Rome, Italy

2. Department of Chemistry, University of South Florida, Tampa, FL, USA

3. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA

4. Institute of Translational Pharmacology, National Research Council, CNR, Rome, Italy

Funder

The Italian National Antarctic Research Program

Ministry for the Education, University and Scientific Research (MIUR),

US National Science Foundation

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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