Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme-Reference-Cited by-同舟云学术

Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme

Published:2022-06-16 Issue:1 Volume:37 Page:1737-1751
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

El-Dershaby Nada H.¹,El-Hawash Soad A.²,Kassab Shaymaa E.¹³,Dabees Hoda G.¹,Abdel Moneim Ahmed E.⁴,Abdel Wahab Ibrahim A.⁵,Abd-Alhaseeb Mohammad M.⁶,El-Miligy Mostafa M. M.²

Affiliation:

1. Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt

2. Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

3. Department of organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia,Egypt

4. Department of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt

5. Microbiology and Immunology Department, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt

6. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhur University, Damanhour, Egypt

Funder

We have no grant or fund. All of us are from non-profit government universities. This article is self funded so we request to waive publishing fees if possible. Thank you

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2086868

Reference78 articles.

1. Prostaglandin E2 synthesis and secretion: The role of PGE2 synthases

2. Prostaglandin E2promotes degranulation-independent release of MCP-1 from mast cells

3. Regulation of Immune Responses by Prostaglandin E2

4. Prostaglandin E2Suppresses Bacterial Killing in Alveolar Macrophages by Inhibiting NADPH Oxidase

5. PGE2-Driven Induction and Maintenance of Cancer-Associated Myeloid-Derived Suppressor Cells

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dual-target inhibitors based on COX-2: a review from medicinal chemistry perspectives;Future Medicinal Chemistry;2023-12

2. Synthesis and Evaluation of Amide Codrug of Ibuprofen and Amlodipine for Dual Inhibition of Inflammation and Hypertension;Research Journal of Pharmacy and Technology;2023-08-31

3. Synthesis, Biological Evaluation, and Computational Studies of 6-Fluoro-3-(Piperidin-4-yl)-1,2-Benzisoxazole Sulfonamide Conjugates;Polycyclic Aromatic Compounds;2023-08-21

4. Edible algae allergenicity – a short report;Journal of Applied Phycology;2022-11-26

5. Thymoquinone counteracts oxidative and inflammatory machinery in carrageenan-induced murine paw edema model;Environmental Science and Pollution Research;2022-10-03