Discovery and SAR analysis of 5-chloro-4-((substituted phenyl)amino)pyrimidine bearing histone deacetylase inhibitors-Reference-Cited by-同舟云学术

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Discovery and SAR analysis of 5-chloro-4-((substituted phenyl)amino)pyrimidine bearing histone deacetylase inhibitors

Published:2022-07-14 Issue:1 Volume:37 Page:1918-1927
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Zhang Lin¹,Chen Yiming²,Li Fahui¹,Zhang Lihui³,Feng Jinhong⁴,Zhang Lei¹

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Weifang Medical University, Weifang, China

2. School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

3. School of Stomatology, Weifang Medical University, Weifang, China

4. Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of sciences), Jinan, China

Funder

Natural Foundation of Shandong Province

Science and Technology Support Plan for Youth Innovation in Universities of Shandong Province

Ideological and Political Project of Weifang University

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2097446

Reference17 articles.

1. Genomewide studies of histone deacetylase function in yeast

2. Histone deacetylases (HDACs): characterization of the classical HDAC family

3. Dissecting the Biological Functions of Drosophila Histone Deacetylases by RNA Interference and Transcriptional Profiling

4. Trend of Histone Deacetylase Inhibitors in Cancer Therapy: Isoform Selectivity or Multitargeted Strategy

5. Thioether-based 2-aminobenzamide derivatives: Novel HDAC inhibitors with potent in vitro and in vivo antitumor activity

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1. Design, Synthesis, Drug-Likeness, anti-Inflammatory, Antimicrobial Activity, and Molecular Docking Studies of Pyrimidine Analogs;Polycyclic Aromatic Compounds;2024-04

2. Emerging therapeutic strategies in cancer therapy by HDAC inhibition as the chemotherapeutic potent and epigenetic regulator;Medical Oncology;2024-03-05

3. Recent Developments of Hydroxamic Acid Hybrids as Potential Anti-Breast Cancer Agents;Future Medicinal Chemistry;2024-01-31

4. Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency;European Journal of Medicinal Chemistry;2023-12

5. Design, Synthesis and Biological Evaluation of Histone Deacetylase Inhibitors Based on Pyrrolo[2,3‐d]pyrimidine and Pyrrolo[2,3‐b]pyridine Scaffolds;ChemMedChem;2023-06-26

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