Design and biological evaluation of substituted 5,7-dihydro-6<i>H</i>-indolo[2,3-<i>c</i>]quinolin-6-one as novel selective Haspin inhibitors-Reference-Cited by-同舟云学术

Design and biological evaluation of substituted 5,7-dihydro-6H-indolo[2,3-c]quinolin-6-one as novel selective Haspin inhibitors

Published:2022-06-07 Issue:1 Volume:37 Page:1632-1650
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Avula Sreenivas¹,Peng Xudan¹,Lang Xingfen¹,Tortorella Micky¹²,Josselin Béatrice³⁴,Bach Stéphane³⁴,Bourg Stephane⁵,Bonnet Pascal⁵,Buron Frédéric⁵,Ruchaud Sandrine³,Routier Sylvain⁵,Neagoie Cleopatra¹²

Affiliation:

1. Guangzhou Institute of Biomedicine and Health, Chinese Academy of Science, Guangzhou, China

2. Centre for Regenerative Medicine and Health, Hong Kong Institute of Science and Innovation, Chinese Academy of Science, Hong Kong SAR, China

3. Sorbonne Université/CNRS UMR8227, Roscoff cedex, France

4. Sorbonne Université/CNRS FR2424, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening Facility), Roscoff cedex, France

5. Institut de Chimie Organique et Analytique, Université d’Orléans, UMR CNRS 7311, Orleans, France

Funder

La Ligue contre le Cancer du Grand Ouest

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2082419

Reference36 articles.

1. Marine Natural Products in Medicinal Chemistry

2. Kinase Inhibitors of Marine Origin

3. Natural Products as a Source of Protein Kinase Activators and Inhibitors

4. Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine

5. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy

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