New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies-Reference-Cited by-同舟云学术

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies

Published:2021-12-27 Issue:1 Volume:37 Page:403-416
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Elkady Hazem¹,Elwan Alaa¹,El-Mahdy Hesham A.²,Doghish Ahmed S.³,Ismail Ahmed²,Taghour Mohammed S.¹,Elkaeed Eslam B.⁴,Eissa Ibrahim H.¹,Dahab Mohammed A.¹,Mahdy Hazem A.¹,Khalifa Mohamed M.¹

Affiliation:

1. Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

2. Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

3. Biochemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr, Egypt

4. Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia

Funder

AlMaarefa University

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.2015343

Reference54 articles.

1. Angiogenesis in cancer, vascular, rheumatoid and other disease

2. Tumor angiogenesis: past, present and the near future

3. Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor

4. Molecular targeted therapy: Treating cancer with specificity

5. A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy

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