Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies-Reference-Cited by-同舟云学术

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies

Published:2021-12-11 Issue:1 Volume:37 Page:299-314
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Khalifa Mohamed M.¹,Al-Karmalawy Ahmed A.²,Elkaeed Eslam B.³,Nafie Mohamed S.⁴^ORCID,Tantawy Mohamed A.⁵⁶,Eissa Ibrahim H.¹,Mahdy Hazem A.¹

Affiliation:

1. Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

2. Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt

3. Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia

4. Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt

5. Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Egypt

6. Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Cairo, Egypt

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.2007905

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4. Molecular modelling of mebendazole polymorphs as a potential colchicine binding site inhibitor

5. Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies

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