Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents-Reference-Cited by-同舟云学术

Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

Published:2017-01-01 Issue:1 Volume:32 Page:600-613
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Eldehna Wagdy M.¹,Almahli Hadia¹²,Al-Ansary Ghada H.³,Ghabbour Hazem A.⁴,Aly Mohamed H.⁵⁶,Ismael Omnia E.⁷,Al-Dhfyan Abdullah⁸,Abdel-Aziz Hatem A.⁹

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt;

2. Department of Chemistry, Faculty of Pharmacy, University of Oxford, Oxford, UK;

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Abbassia, Egypt;

4. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;

5. Department of Pharmacology and Toxicology, Faculty of Pharmacy, British University in Egypt, Cairo, Egypt;

6. Department of Biology, The American University in Cairo, New Cairo, Egypt;

7. Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt;

8. Stem Cell & Tissue Re-Engineering Program, Research Center, King Faisal Specialized Hospital & Research Center, Riyadh, Saudi Arabia;

9. Department of Applied Organic Chemistry, National Research Center, Dokki, Giza, Egypt

Funder

Deanship of Scientific Research at King Saud University

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://tandfonline.com/doi/pdf/10.1080/14756366.2017.1279155

Reference62 articles.

1. Mechanisms of Cancer Drug Resistance

2. Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2H-chromene derivatives as potent anti-breast cancer agents

3. Molecular portraits of breast cancer: tumour subtypes as distinct disease entities

4. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

5. Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles

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