Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity

Author:

El-Damasy Ashraf K.12,Jin Heewon1,Park Jung Woo3,Kim Hyun Ji1,Khojah Hanan4,Seo Seon Hee5,Lee Ju-Hyeon1,Bang Eun-Kyoung1,Keum Gyochang16

Affiliation:

1. Center for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea

2. Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

3. Center for Supercomputing Applications, Div. of National Supercomputing R&D, Korea Institute of Science and Technology Information, Daejeon, Republic of Korea

4. Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia

5. Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea

6. Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology (UST), Seoul, Republic of Korea

Funder

National Research Council of Science & Technology

Korean government

Institutional Program grant by the Korea Institute of Science and Technology

the Korea Research Fellowship Program grant through NRF funded by the Ministry of Science and ICT

Korea Institute of Science and Technology Information (KISTI) Institutional Program

National Cancer Institute

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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