Discovery of Klotho peptide antagonists against Wnt3 and Wnt3a target proteins using combination of protein engineering, protein–protein docking, peptide docking and molecular dynamics simulations
Author:
Affiliation:
1. Department of Biophysics, School of Medicine, Bahcesehir University (BAU), Istanbul, Turkey;
2. Department of Biosciences, COMSATS Institute of Information Technology (CIIT), Islamabad, Pakistan
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2016.1235569
Reference60 articles.
1. The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS
2. Mutation of the mouse klotho gene leads to a syndrome resembling ageing
3. Stem cells, ageing and the quest for immortality
4. Suppression of Aging in Mice by the Hormone Klotho
5. Klotho
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