Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies

Author:

Alanazi Mohammed M.1ORCID,Elwan Alaa2ORCID,Alsaif Nawaf A.1ORCID,Obaidullah Ahmad J.1ORCID,Alkahtani Hamad M.1ORCID,Al-Mehizia Abdulrahman A.1ORCID,Alsubaie Sultan M.1,Taghour Mohammed S.2ORCID,Eissa Ibrahim H.2ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

2. Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference85 articles.

1. AACR Cancer Progress Report 2015

2. WHO. Cancer. Available from: https://www.who.int/health-topics/cancer#tab=tab_1. [accessed May 2020].

3. Chemistry and Pharmacology of Anticancer Drugs

4. The ErbB/HER family of protein-tyrosine kinases and cancer

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