Structure–activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease-Reference-Cited by-同舟云学术

Structure–activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease

Published:2021-01-01 Issue:1 Volume:36 Page:1860-1873
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Wu Chengyao¹,Zhang Guijuan²,Zhang Zai-Wei³,Jiang Xia¹,Zhang Ziwen¹,Li Huanhuan¹,Qin Hua-Li³,Tang Wenjian¹

Affiliation:

1. School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China

2. Management Center of Anhui Continuing Education Network Park, Anhui Open University, Hefei, China

3. School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China

Funder

National Natural Science Funding of China

Natural Science Foundation of Anhui provincial Department of Education

Anhui Provincial Natural Science Foundation

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1959571

Reference61 articles.

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4. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

5. Early A accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

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