Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis-Reference-Cited by-同舟云学术

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Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis

Published:2021-01-01 Issue:1 Volume:36 Page:914-921
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Dostál Jiří¹,Brynda Jiří¹,Vaňková Lucie²,Zia Syeda Rehana³,Pichová Iva¹^ORCID,Heidingsfeld Olga¹⁴,Lepšík Martin¹^ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic

2. Laboratory of Ligand Engineering, Institute of Biotechnology, Czech Academy of Sciences, v.v.i., BIOCEV Research Center, Vestec, Czech Republic

3. Department of Chemistry, University of Karachi, Karachi, Pakistan

4. Department of Biochemistry, Faculty of Science, Charles University in Prague, Prague, Czech Republic

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1906664

Reference47 articles.

1. Candida parapsilosis: from Genes to the Bedside

2. Antifungals: Mechanism of Action and Drug Resistance

3. Association of Fluconazole Pharmacodynamics with Mortality in Patients with Candidemia

4. Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

5. Secreted proteins of Candida albicans

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1. Estimating the expression levels of genes controlling biofilm formation and evaluating the effects of different conditions on biofilm formation and secreted aspartic proteinase activity in Candida albicans and Saccharomyces cerevisiae: a comparative study;Beni-Suef University Journal of Basic and Applied Sciences;2024-05-24

2. Secreted Aspartic Proteinases: Key Factors in Candida Infections and Host-Pathogen Interactions;International Journal of Molecular Sciences;2024-04-27

3. Homology Modeling and Analysis of Vacuolar Aspartyl Protease from a Novel Yeast Expression Host Meyerozyma guilliermondii Strain SO;Arabian Journal for Science and Engineering;2022-08-09

4. Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors;Medical Mycology;2021-09-10

5. Inhibition of Ras1-MAPK pathways for hypha formation by novel drug candidates in Candida albicans;2021-07-06

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