Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

Author:

Abutaleb Nader S.1,Elhassanny Ahmed E. M.1,Nocentini Alessio2ORCID,Hewitt Chad S.3,Elkashif Ahmed4,Cooper Bruce R.5,Supuran Claudiu T.2ORCID,Seleem Mohamed N.16ORCID,Flaherty Daniel P.378ORCID

Affiliation:

1. Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VI, USA

2. Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Firenze, Italy

3. Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN, USA

4. Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA

5. Metabolite Profiling Facility, Bindley Bioscience Center, Purdue University, West Lafayette, Indiana, United States

6. Center for Emerging, Zoonotic and Arthropod-borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VI, USA

7. Purdue Institute for Drug Discovery, West Lafayette, IN, USA

8. Purdue Institute of Inflammation, Immunology and Infectious Disease, West Lafayette, IN, USA

Funder

Italian Ministry for University and Research

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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