New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011–2021) focussing on structure–activity relationship (SAR) and docking insights-Reference-Cited by-同舟云学术

New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011–2021) focussing on structure–activity relationship (SAR) and docking insights

Published:2021-01-01 Issue:1 Volume:36 Page:1572-1600
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Elkamhawy Ahmed¹²,Ali Eslam M. H.³⁴⁵,Lee Kyeong¹

Affiliation:

1. College of Pharmacy, Dongguk University-Seoul, Goyang, Republic of Korea

2. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

3. Center for Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Republic of Korea;

4. University of Science & Technology (UST), Daejeon, Republic of Korea

5. Pharmaceutical Chemistry Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo, Egypt

Funder

National Research Foundation of Korea

Korea government

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2021.1937143

Reference110 articles.

1. Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion

2. Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation

3. A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

4. Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy

5. Exploration of the therapeutic aspects of Lck: A kinase target in inflammatory mediated pathological conditions

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