Novel dual-targeting inhibitors of NSD2 and HDAC2 for the treatment of liver cancer: structure-based virtual screening, molecular dynamics simulation, and <i>in vitro</i> and <i>in vivo</i> biological activity evaluations-Reference-Cited by-同舟云学术

Novel dual-targeting inhibitors of NSD2 and HDAC2 for the treatment of liver cancer: structure-based virtual screening, molecular dynamics simulation, and in vitro and in vivo biological activity evaluations

Published:2023-12-07 Issue:1 Volume:39 Page:
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Jin Xing¹,Wang Yuting²,Chen Jing¹,Niu Miaomiao²,Yang Yang¹,Zhang Qiaoxuan³⁴,Bao Guangyu¹

Affiliation:

1. Department of Laboratory Medicine, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China

2. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China

3. Department of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, China

4. State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

Funder

Guangzhou Science and Technology Plan Projects

Young Talents Program” of Guangdong Academy of Traditional Chinese Medicine

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2023.2289355

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