New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAF <sup>V600E</sup> and EGFR inhibitors celecoxib analogs: design, synthesis, anti-inflammatory/anti-proliferative activities, apoptosis and molecular modeling study-Reference-Cited by-同舟云学术

New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAF ^V600E and EGFR inhibitors celecoxib analogs: design, synthesis, anti-inflammatory/anti-proliferative activities, apoptosis and molecular modeling study

Published:2023-12-07 Issue:1 Volume:38 Page:
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Fadaly Wael A. A.¹,Nemr Mohamed T. M.²,Zidan Taha H.¹,Mohamed Fatma E. A.¹,Abdelhakeem Marwa M.¹,Abu Jayab Nour N.³,Omar Hany A.³⁴,Abdellatif Khaled R. A.¹⁵

Affiliation:

1. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

2. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt

3. Sharjah Institute for Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

4. Pharmacology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

5. Pharmaceutical Sciences Department, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2023.2290461

Reference81 articles.

1. Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates

2. Correlation between Strength of Estrogen Receptor positivity and Outcome of Adjuvant Tamoxifen Therapy in Breast Cancer Patients

3. Tamoxifen for Breast Cancer

4. Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold

5. Structural basis for androgen specificity and oestrogen synthesis in human aromatase

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