Mixed and non-competitive enzyme inhibition: underlying mechanisms and mechanistic irrelevance of the formal two-site model

Author:

Pesaresi Alessandro1

Affiliation:

1. Istituto di Cristallografia – Consiglio Nazionale delle Ricerche, Trieste, Italy

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference63 articles.

1. Recommendations 1981;Symbolism and terminology in enzyme kinetics;Biochem J,1983

2. ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism

3. Evaluation of Enzyme Inhibitors in Drug Discovery

4. Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase

5. Copeland RA, Anderson PS. Enzymes and Enzyme Inhibitors” in Textbook of Drug Design and Discovery. 3rd ed., P. Krogsgaard-Larsen, T. Liljefors, U. Madsen, editors. New York: Taylor and Francis; 2002

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