Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase-Reference-Cited by-同舟云学术

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase

Published:2023-05-29 Issue:1 Volume:38 Page:
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Hassan Ahmed H. E.¹²^ORCID,Oh Yeon Il³,Lee Chae Hyeon⁴,Kim Yeon Ju⁴,Cho Soo Bin⁴,Alam Md. Maqusood³,Park Sang-Eun⁵⁶,Chung Kyung-Sook⁵,Lee Kyung-Tae⁵⁶^ORCID,Lee Yong Sup²³⁴^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

2. Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea

3. Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea

4. Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea

5. Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea

6. Department of Life and Biomedical and Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2023.2217695

Reference36 articles.

1. Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity

2. Fluorinated CRA13 analogues: Synthesis, in vitro evaluation, radiosynthesis, in silico and in vivo PET study

3. Antiproliferative 3-deoxysphingomyelin analogs: Design, synthesis, biological evaluation and molecular docking of pyrrolidine-based 3-deoxysphingomyelin analogs as anticancer agents

4. Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani

5. Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents

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