Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds
Author:
Affiliation:
1. Pharmaceutical Organic Chemistry Department, Helwan University, Helwan, Cairo, Egypt;
2. Biochemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Cairo, Egypt
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2018.1461854
Reference49 articles.
1. Epidemiology of and Risk Factors for Type 2 Diabetes in Egypt
2. Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4
3. Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization
4. The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes
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