Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors-Reference-Cited by-同舟云学术

Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors

Published:2018-01-01 Issue:1 Volume:33 Page:651-656
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Xin Minhang¹,Duan Weiming¹,Feng Yifan¹,Hei Yuan-Yuan¹,Zhang Hao¹,Shen Ying¹,Zhao Hong-Yi¹,Mao Shuai¹,Zhang San-Qi¹

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an, P.R. China

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2018.1444608

Reference20 articles.

1. Targeting the phosphoinositide 3-kinase pathway in cancer

2. Present and Future of PI3K Pathway Inhibition in Cancer: Perspectives and Limitations

3. Targeting PI3Kδ: Emerging Therapy for Chronic Lymphocytic Leukemia and Beyond

4. Targeting the B cell receptor pathway in chronic lymphocytic leukemia

5. PI3Kδ Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic

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