Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors

Author:

Mahnashi Mater H.1,Nahari Mohammed2,Almasoudi Hassan2,Alhasaniah Abdulaziz2,Elgazwi Sara3,Abou-Salim Mahrous A.4

Affiliation:

1. Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia

2. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia

3. Department of Chemistry, University of Derna, Derna, Libya

4. Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt

Funder

Deputy for Research and Innovation Ministry of Education

Publisher

Informa UK Limited

Reference91 articles.

1. WHO. Cancer. [cited 2024 Mar 18]. Available from: https://www.who.int/

2. WHO. Global cancer burden growing amidst mounting need for services. [cited 2024 Mar 18]. Available from: https://www.who.int/

3. Counting the social, psychological, and economic costs of COVID-19 for cancer patients

4. NCI. Angiogenesis inhibitors. [cited 2024 Mar 18]. Available from: https://www.cancer.gov/

5. Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

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