Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

Author:

Firoozpour Loghman1,Gao Lixin2,Moghimi Setareh1,Pasalar Parvin3,Davoodi Jamshid4,Wang Ming-Wei2,Rezaei Zahra5,Dadgar Armin6,Yahyavi Hoda1,Amanlou Massoud5ORCID,Foroumadi Alireza15

Affiliation:

1. Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

2. National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

3. Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

4. Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran

5. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

6. Pharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Funder

National Health and Family Planning Commission of China

Shanghai Science and Technology Development Fund

Thousand Talents Program in China

Iran National Science Foundation

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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