Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities-Reference-Cited by-同舟云学术

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities

Published:2020-10-26 Issue:1 Volume:36 Page:15-33
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Shawky Ahmed M.¹,Ibrahim Nashwa A.²,Abourehab Mohammed A. S.³,Abdalla Ashraf N.⁴,Gouda Ahmed M.²⁵^ORCID

Affiliation:

1. Science and Technology Unit (STU), Umm Al-Qura University, Makkah, Saudi Arabia

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

3. Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

4. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

5. Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

Funder

National Science, Technology and Innovation Plan

King Abdulaziz City for Science and Technology

Kingdom of Saudi Arabia

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2020.1837124

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2. Kinase-targeted cancer therapies: progress, challenges and future directions

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