Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain

Author:

Yang Hak Kyun1,Son Woo Seung12,Lim Keon Seung3,Kim Gun Hee4,Lim Eun Jeong1,Gadhe Changdev G.1,Lee Jae Yeol4,Jeong Kyu-Sung2,Lim Sang Min15ORCID,Pae Ae Nim16ORCID

Affiliation:

1. Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Seoul, Republic of Korea;

2. Department of Chemistry, Yonsei University, Seoul, Republic of Korea;

3. 1ST Biotherapeutics Inc., Seongnam, Gyeonggi-do, Republic of Korea;

4. Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul, Republic of Korea;

5. Division of Bio-Medical Science and Technology, Korea University of Science and Technology, Daejon, Republic of Korea;

6. Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Republic of Korea

Funder

Korea government

National Research Council of Science & Technology

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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