Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism

Author:

Lopes Priscila Hess1,Murakami Mário T.2,Portaro Fernanda C. V.1,Mesquita Pasqualoto Kerly Fernanda3,van den Berg Carmen4,Tambourgi Denise V.1

Affiliation:

1. Immunochemistry Laboratory, Butantan Institute, São Paulo, SP, Brazil;

2. Biosciences National Laboratory, National Centre for Research in Energy and Materials, Campinas, SP, Brazil;

3. Alchemy – Innovation, Research & Development Ltda., Center of Innovation, Entrepreneurship and Technology (CIETEC), University of São Paulo, SP, Brazil;

4. Centre for Medical Education, Cardiff University, School of Medicine, Cardiff, United Kingdom

Funder

INCTTox-FAPESP

Centre of Toxins, Immune Response and Cell Signalling/São Paulo Research Foundation (CeTICS/FAPESP)

CAPES and FAPESP to Priscila Hess Lopes

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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