C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

Author:

Felicetti Tommaso1,Mangiaterra Gianmarco2,Cannalire Rolando1ORCID,Cedraro Nicholas2,Pietrella Donatella3ORCID,Astolfi Andrea1,Massari Serena1ORCID,Tabarrini Oriana1ORCID,Manfroni Giuseppe1ORCID,Barreca Maria Letizia1ORCID,Cecchetti Violetta1ORCID,Biavasco Francesca2ORCID,Sabatini Stefano1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Chemistry and Technology of the Drug Section, Università degli Studi di Perugia, Perugia, Italy

2. Department of Life and Environmental Sciences, Università Politecnica delle Marche, Ancona, Italy

3. Department of Pharmaceutical Sciences, Biochemical Sciences and Health Section, Università degli Studi di Perugia, Perugia, Italy

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference42 articles.

1. Ten threats to global health in 2019. Available from: https://www.who.int/emergencies/ten-threats-to-global-health-in-2019 [last accessed 7 Apr 2019].

2. Recent advances toward a molecular mechanism of efflux pump inhibition

3. Understanding the basis of antibiotic resistance: a platform for drug discovery

4. Antibiotic Adjuvants: Rescuing Antibiotics from Resistance

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