Inhibition of cell proliferation, invasion and migration by the cardenolides digitoxigenin monodigitoxoside and convallatoxin in human lung cancer cell line

Author:

Schneider Naira F. Z.1,Geller Fabiana C.1,Persich Lara1,Marostica Lucas L.1,Pádua Rodrigo M.2,Kreis Wolfgang3,Braga Fernão C.2,Simões Cláudia M. O.1

Affiliation:

1. Departamento de Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

2. Faculdade de Farmácia, Departamento de Produtos Farmacêuticos, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

3. Department of Biology, Friedrich-Alexander Universität, Erlangen-Nürnberg, Germany

Funder

Brazilian agency CNPq/MCTI

Marie Curie Foundation

Publisher

Informa UK Limited

Subject

Organic Chemistry,Plant Science,Biochemistry,Analytical Chemistry

Reference22 articles.

1. Antiherpes activity of glucoevatromonoside, a cardenolide isolated from a Brazilian cultivar of Digitalis lanata

2. Isolation of cardenolides from a Brazilian cultivar of Digitalis lanata by rotation locular counter-current chromatography

3. Carvalho A. 2012. Avaliação dos efeitos citotóxicos de cardenolídeos em células tumorais [Evaluation of cytotoxic effectos of cardenolides in tumor cells] [dissertation]. Florianopolis (BR): Federal University of Santa Catarina. p. 126.

4. Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides

5. Cancer invasion and metastasis: changing views

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