Thrombin-induced platelet inhibition by 2′,4′-dihydroxychalcone and 2′,4′-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from <i>Empetrum nigrum</i>-Reference-Cited by-同舟云学术

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Thrombin-induced platelet inhibition by 2′,4′-dihydroxychalcone and 2′,4′-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum

Published:2024-04-03 Issue: Volume: Page:1-9
ISSN:1478-6419
Container-title:Natural Product Research
language:en
Short-container-title:Natural Product Research

Author:

Fock Ekaterina¹,Pronin Nikita²,Rukoyatkina Natalia¹,Whaley Anastasiia¹²,Gambaryan Stepan¹,Whaley Andrei²^ORCID

Affiliation:

1. Laboratory of Cellular Mechanisms of Blood Homeostasis, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint Petersburg, Russia

2. Department of Pharmacognosy, Saint Petersburg State Chemical and Pharmaceutical University, Saint Petersburg, Russia

Funder

Russian Science Foundation

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/14786419.2024.2334882

Reference37 articles.

1. Dipyridamole Enhances NO/cGMP-Mediated Vasodilator-Stimulated Phosphoprotein Phosphorylation and Signaling in Human Platelets

2. Dual Antiplatelet Therapy with Parenteral P2Y12 Inhibitors: Rationale, Evidence, and Future Directions

3. Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS

5. Venous thromboembolism

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