Study on the potential hypoglycemic flavonoids in Abrus precatorius leaves: purification process, quality profile and activity mechanisms by transcriptomics and network pharmacology

Author:

Yuan Xujiang1ORCID,Xue Xianmei1,Liang Zhike1,He Cuimin1

Affiliation:

1. Center for Drug Research and Development/Class III Laboratory of Modern Chinese Medicine Preparation, State Administration of Traditional Chinese Medicine of the P.R.C/ Key Laboratory of modern Chinese medicine of Education Department of Guangdong Province/Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems/ Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou, P R China

Funder

Natural Science Foundation of Guangdong Province

Medical Science and Technology Foundation of Guangdong Province

Publisher

Informa UK Limited

Reference20 articles.

1. Antihyperglycemic and insulin secretagogue activities of Abrus precatorius leaf extract;Balekari U;Pharmacogn Res,2016

2. Glucose lowering and pancreato-protective effects of Abrus Precatorius (L.) leaf extract in normoglycemic and STZ/Nicotinamide-Induced diabetic rats;Boye A;J Ethnopharmacol,2020

3. Bioguided fractionation and isolation of natural inhibitors of advanced glycation end-products (AGEs) from Calophyllum flavoramulum

4. Quality analysis of the leaves of Abrus precatorius based on HPLC fingerprints and chemical pattern recognition;He CM;Chin Tradit Pat Med,2021

5. UPLC-MS fingerprints, phytochemicals and quality evaluation of flavonoids from Abrus precatorius leaves

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