Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM)
Author:
Affiliation:
1. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO, USA
Funder
National Institutes of Health
Publisher
Informa UK Limited
Subject
Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10409238.2021.1925218
Reference139 articles.
1. Kinetic and Catalytic Mechanisms of Protein Kinases
2. Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.
3. Dna2 of Saccharomyces cerevisiae Possesses a Single-stranded DNA-specific Endonuclease Activity That Is Able to Act on Double-stranded DNA in the Presence of ATP
4. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
5. Dominant TEL1-hy Mutations Compensate for Mec1 Lack of Functions in the DNA Damage Response
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1. Phosphoregulation of the checkpoint kinase Mec1ATR;DNA Repair;2023-09
2. Dynamic Properties of the DNA Damage Response Mre11/Rad50 Complex;International Journal of Molecular Sciences;2023-08-03
3. Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology;Cell Reports;2023-07
4. Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology;2023-05-03
5. A DNA damage–induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A;Proceedings of the National Academy of Sciences;2023-03-30
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