Small molecule-regulated switches to provide functional control of CAR T cells within the patient-Reference-Cited by-同舟云学术

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Small molecule-regulated switches to provide functional control of CAR T cells within the patient

Published:2024-06-02 Issue:6 Volume:24 Page:425-432
ISSN:1471-2598
Container-title:Expert Opinion on Biological Therapy
language:en
Short-container-title:Expert Opinion on Biological Therapy

Author:

Zajc Charlotte U.¹²,Sylvander Elise²³,Lehner Manfred²³⁴,Traxlmayr Michael W.¹²

Affiliation:

1. Department of Chemistry, Institute of Biochemistry, BOKU University, Vienna, Austria

2. CD Laboratory for Next Generation CAR T Cells, Vienna, Austria

3. St. Anna Children´s Cancer Research Institute, CCRI, Vienna, Austria

4. Department of Pediatrics, St. Anna Kinderspital, Medical University of Vienna, Vienna, Austria

Funder

Austrian Science Fund

Cancer Research Institute

DOC Fellowship of the Austrian Academy of Sciences at the St. Anna Children´s Cancer Research Institute

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/14712598.2024.2371034

Reference53 articles.

1. Long-term outcomes following CAR T cell therapy: what we know so far

2. Remote control of therapeutic T cells through a small molecule–gated chimeric receptor

3. Recent advances and limitations of mTOR inhibitors in the treatment of cancer

4. Human antibody-based chemically induced dimerizers for cell therapeutic applications

5. Switchable assembly and function of antibody complexes in vivo using a small molecule

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