Thymosin β4 inhibits PDGF-BB induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain
Author:
Affiliation:
1. Lipid Research Laboratory, VA Medical Center, Washington, DC, USA
2. Department of Biochemistry and Molecular Medicine, The George Washington University Medical Center, Washington, DC, USA
Funder
National Institute on Alcohol Abuse and Alcoholism
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology
Link
https://www.tandfonline.com/doi/pdf/10.1080/14712598.2018.1478961
Reference24 articles.
1. Liver fibrosis
2. Pathophysiology of Alcoholic Liver Disease
3. Hepatic Stellate Cells
4. TGF-β1 Up-Regulates the Expression of PDGF-β Receptor mRNA and Induces a Delayed PI3K-, AKT-, and p70S6K-Dependent Proliferative Response in Activated Hepatic Stellate Cells
5. Thymosin β: actin-sequestering protein moonlights to repair injured tissues
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