Addressing high dose AAV toxicity – ‘one and done’ or ‘slower and lower’?
Author:
Affiliation:
1. Selecta Biosciences, Watertown, MA, USA
2. Gene Therapy Center and Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology
Link
https://www.tandfonline.com/doi/pdf/10.1080/14712598.2022.2060737
Reference36 articles.
1. Food and Drug Administration (FDA) Cellular, Tissue, and Gene Therapies Advisory Committee (CTGTAC) meeting #70 brief document. [cited 2022 Feb 25]. Available from: www.fdagov/media/151599/download
2. Emerging Issues in AAV-Mediated In Vivo Gene Therapy
3. Revisiting the “New” Inflammatory Toxicities of Adeno-Associated Virus Vectors
4. Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
5. Gene Therapy: It Is Time to Talk about High-Dose AAV
Cited by 86 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Delivery of CRISPR/Cas9 system by AAV as vectors for gene therapy;Gene;2024-11
2. Limb Perfusion Delivery of a rAAV1 Alpha-1 Antitrypsin Vector in Non-Human Primates Is Safe but Insufficient for Therapy;Genes;2024-09-10
3. CRISPR-Cas9-mediated genome editing delivered by a single AAV9 vector inhibits HSV-1 reactivation in a latent rabbit keratitis model;Molecular Therapy - Methods & Clinical Development;2024-09
4. Modulation of AAV9 Galactose Binding Yields Novel Gene Therapy Vectors and Predicts Cross-Species Differences in Glycan Avidity;Human Gene Therapy;2024-08-13
5. Membrane chromatography for AAV full capsid enrichment: Process development to scale up;Journal of Chromatography B;2024-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3