1. Faulty of Medicine, University of Southampton, Southampton, UK
2. Merck Exploratory Science Center, Merck Research Laboratories, Cambridge, MA, USA
3. Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK
4. NIHR Southampton Biomedical Research Centre, University Hospital Southampton Foundation NHS Trust, Southampton SO16 6YD, UK
5. Global Health Research Institute, University of Southampton, Southampton SO17 1BJ, UK