Exploring thresholds and interaction effects among antibiotic usage, covariates, and their effect on antibiotic resistance using an extended-spectrum β-Lactamase–producing Klebsiella pneumoniae case

Author:

Aldeyab Mamoon A.1ORCID,Al-Hashimy Zainab Said12,Al-Yaqoobi Mubarak3,Conway Barbara R.14ORCID,Darwish Elhajji Feras5,Bond Stuart E.16,Lattyak Elizabeth A.7,Hasan Syed Shahzad1ORCID,Lattyak William J.7

Affiliation:

1. Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK

2. Directorate of Pharmacy and Medical Stores, Khawlah Hospital, Muscat, Oman

3. Directorate of Laboratories, Department of Microbiology, Khawlah Hospital, Muscat, Oman

4. Institute of Skin Integrity and Infection Prevention, University of Huddersfield, Huddersfield, UK

5. Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan

6. Pharmacy Department, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK

7. Statistical Consulting Department, Scientific Computing Associates Corp, River Forest, IL, USA

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Microbiology (medical),Microbiology

Reference71 articles.

1. Global Antibiotics Use and Resistance

2. O’Neill J Antimicrobial Resistance: tackling a crisis for the health and wealth of nations. The Review on Antimicrobial Resistance. 2014. (cited 6 Aug 2022). Available online: https://amr-review.org/Publications.html

3. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

4. Antibacterial resistance worldwide: causes, challenges and responses

5. Origins and Evolution of Antibiotic Resistance

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