Identification and characterization of novel hydrolytic degradation products of netarsudil by LC-Q-TOF-MS/MS: In silico toxicity prediction
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, Jawaharlal Nehru Technological University Anantapur, Anantapuram, India
2. Raghavendra Institute of Pharmaceutical Education and Research, Anantapuram, India
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Pharmaceutical Science,Biochemistry,Analytical Chemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10826076.2022.2089999
Reference20 articles.
1. Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040
2. Netarsudil Ophthalmic Solution 0.02%: First Global Approval
3. Netarsudil/Latanoprost Fixed-Dose Combination for Elevated Intraocular Pressure: Three-Month Data from a Randomized Phase 3 Trial
4. Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma
5. Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2)
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1. HPLC-DAD method for concurrent estimation of netarsudil, latanoprost and benzalkonium chloride: Stability indicating study, impurity separation, assay of ophthalmic preparations and greenness/whiteness valuation;Microchemical Journal;2024-09
2. Characterization of forced degradation products of Netarsudil: Optimization and validation of stability-indicating RP-HPLC method for simultaneous quantification of process related impurities of Netarsudil;Turkish Journal of Pharmaceutical Sciences;2023-12-25
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