SEPARATION AND ESTIMATION OF PROCESS RELATED IMPURITIES AND DEGRADATION PRODUCTS OF LEVETIRACETAM IN SOLID PHARMACEUTICAL FORMULATION USING ION-PAIR CHROMATOGRAPHY
Author:
Affiliation:
1. a Dr. Reddy's Laboratories Ltd., IPDO, Bachupally , Hyderabad , A.P , India
2. b Department of Chemistry , S.A.S., V.I.T. University , Vellore , Tamilnadu , India
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Pharmaceutical Science,Biochemistry,Analytical Chemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10826076.2012.704606
Reference17 articles.
1. U.S. Food and Drug Administration. Drug Approval Package Keppra (Levetiracetam) Tablets NDA 21035, 1999. http://www.accessdata.fda.gov/drugsatfda_docs/nda/99/21035_Keppra.cfm (Accessed March 2011)
2. Validation of a high-performance thin-layer chromatographic method with densitometric detection for quantitative analysis of two anticonvulsants in tablets
3. Microemulsion electrokinetic chromatography applied for separation of levetiracetam from other antiepileptic drugs in polypharmacy
4. Analysis of the antiepileptic drug keppra by capillary electrophoresis
5. Determination of levetiracetam in human plasma with minimal sample pretreatment
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