Determination of methotrexate, 7-hydroxymethotrexate, and 2,4-diamino-N10-methylpteroic acid by LC–MS/MS in plasma and cerebrospinal fluid and application in a pharmacokinetic analysis of high-dose methotrexate
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA
2. Department of Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA
Funder
National Cancer Institute
Cancer Center Support
American Lebanese Syrian Associated Charities
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Pharmaceutical Science,Biochemistry,Analytical Chemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10826076.2016.1243558
Reference23 articles.
1. High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphoblastic leukemia
2. Carboplatin/Ifosfamide Window Therapy for Osteosarcoma: Results of the St Jude Children’s Research Hospital OS-91 Trial
3. Results of the randomized international FAB/LMB96 trial for intermediate risk B-cell non-Hodgkin lymphoma in children and adolescents: it is possible to reduce treatment for the early responding patients
4. High-Dose Methotrexate in Osteosarcoma: Let the Questions Surcease—Time for Final Acceptance
5. Biology, Risk Stratification, and Therapy of Pediatric Acute Leukemias: An Update
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