A combinatorial approach of a polypharmacological adjuvant 2-deoxy-D-glucose with low dose radiation therapy to quell the cytokine storm in COVID-19 management

Author:

Verma Amit1,Adhikary Amitava2ORCID,Woloschak Gayle3ORCID,Dwarakanath Bilikere S.4ORCID,Papineni Rao V. L.5ORCID

Affiliation:

1. PACT & Health LLC, Branford, CT, USA

2. Department of Chemistry, Oakland University, Rochester, MI, USA;

3. Department of Radiobiology, Northwestern University's Feinberg School of Medicine, Chicago, IL, USA;

4. Department of Research and Development, Shanghai Proton and Heavy Ion Center, Shanghai, People's Republic of China;

5. Department of Surgery, University of Kansas Medical Center (Adjunct), and PACT & Health LLC, Branford, CT, USA

Publisher

Informa UK Limited

Subject

Radiology Nuclear Medicine and imaging,Radiological and Ultrasound Technology

Reference65 articles.

1. SARS-CoV-2 Vaccines: Status Report

2. Balkrishna A, Thakur P, Singh S, Dev SN, Jain V, Varshney A, Sharma RK. 2020. Glucose antimetabolite 2-Deoxy-D-Glucose and its derivative as promising candidates for tackling COVID-19: insights derived from in silico docking and molecular simulations.

3. Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019

4. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

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