Prior irradiation results in elevated programmed cell death protein 1 (PD-1) in T cells-Reference-Cited by-同舟云学术

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Prior irradiation results in elevated programmed cell death protein 1 (PD-1) in T cells

Published:2017-11-29 Issue:5 Volume:94 Page:488-494
ISSN:0955-3002
Container-title:International Journal of Radiation Biology
language:en
Short-container-title:International Journal of Radiation Biology

Author:

Li Deguan¹,Chen Renxiang²,Wang Yi-Wen²,Fornace Albert J.²³,Li Heng-Hong²³

Affiliation:

1. Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China;

2. Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC, USA;

3. Department of Oncology, Georgetown University, Washington, DC, USA

Funder

National Natural Science Foundation of China

CAMS Innovation Fund for Medical Sciences

U.S. Department of Energy

Publisher

Informa UK Limited

Subject

Radiology Nuclear Medicine and imaging,Radiological and Ultrasound Technology

Link

https://www.tandfonline.com/doi/pdf/10.1080/09553002.2017.1400192

Reference31 articles.

1. Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

2. Ionizing Radiation Predisposes Nonmalignant Human Mammary Epithelial Cells to Undergo Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition

3. T cell exhaustion and Interleukin 2 downregulation

4. Program Death-1 Engagement Upon TCR Activation Has Distinct Effects on Costimulation and Cytokine-Driven Proliferation: Attenuation of ICOS, IL-4, and IL-21, But Not CD28, IL-7, and IL-15 Responses

5. PD-1:PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2

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1. MHC-I and PD-L1 Expression is Associated with Decreased Tumor Outgrowth and is Radiotherapy-inducible in the Murine Head and Neck Squamous Cell Carcinoma Model MOC1;Molecular Imaging and Biology;2024-07-15

2. How We Got Here: One Laboratory's Odyssey in the Field of Radiation-Inducible Genes;Radiation Research;2024-04-04

3. The role of radiotherapy in tumor immunity and the potential of PET/CT in detecting the expression of PD-1/PD-L1;Japanese Journal of Radiology;2023-11-13

4. Radiotherapy upregulated immune checkpoints contribute to the development of second primary OSCC;Oral Diseases;2023-05-22

5. Influence of chemoradiation on the immune microenvironment of cervical cancer patients;Strahlentherapie und Onkologie;2022-10-17

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